[{"@context":"https:\/\/schema.org\/","@type":"Article","@id":"https:\/\/www.zipava.sk\/nedostatok-spanku-priama-cesta-k-alzheimerovej-chorobe\/#Article","mainEntityOfPage":"https:\/\/www.zipava.sk\/nedostatok-spanku-priama-cesta-k-alzheimerovej-chorobe\/","headline":"Nedostatok sp\u00e1nku – priama cesta k Alzheimerovej chorobe","name":"Nedostatok sp\u00e1nku – priama cesta k Alzheimerovej chorobe","description":"V prvej \u0161t\u00fadii, ktor\u00e1 sa uskuto\u010dnila na univerzite v meste Wisconsin-Madison, sa z\u00fa\u010dastnilo 101 \u013eud\u00ed s priemern\u00fdm vekom 63 rokov. Ka\u017ed\u00fd mal norm\u00e1lne myslenie, pam\u00e4\u0165 a fyzick\u00e9 zru\u010dnosti, ale ka\u017ed\u00fd bol vy\u0161etrovan\u00fd na ot\u00e1zku, \u010di riziko vzniku Alzheimerovej choroby: \u010di rodi\u010dia trpia chorobou alebo \u010di existuje \u0161pecifick\u00fd g\u00e9n APOE. \u00da\u010dastn\u00edci diskutovali o kvalite sp\u00e1nku a […]","datePublished":"2018-09-09","dateModified":"2018-09-09","author":{"@type":"Person","@id":"https:\/\/www.zipava.sk\/author\/#Person","name":"zipava.sk\n","url":"https:\/\/www.zipava.sk\/author\/","identifier":1,"image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/bbaa4e9a58aac4329fe0ade0f3fb816f09f0dc43c21f6e884dccfbc124b16b29?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/bbaa4e9a58aac4329fe0ade0f3fb816f09f0dc43c21f6e884dccfbc124b16b29?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"zipava.sk","logo":{"@type":"ImageObject","@id":"\/logo.png","url":"\/logo.png","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/www.zipava.sk\/wp-content\/uploads\/img_a293069_w16488_t1541777832.jpg","url":"https:\/\/www.zipava.sk\/wp-content\/uploads\/img_a293069_w16488_t1541777832.jpg","height":0,"width":0},"url":"https:\/\/www.zipava.sk\/nedostatok-spanku-priama-cesta-k-alzheimerovej-chorobe\/","about":["Zdravie"],"wordCount":381,"articleBody":"\t\tV prvej \u0161t\u00fadii, ktor\u00e1 sa uskuto\u010dnila na univerzite v meste Wisconsin-Madison, sa z\u00fa\u010dastnilo 101 \u013eud\u00ed s priemern\u00fdm vekom 63 rokov. Ka\u017ed\u00fd mal norm\u00e1lne myslenie, pam\u00e4\u0165 a fyzick\u00e9 zru\u010dnosti, ale ka\u017ed\u00fd bol vy\u0161etrovan\u00fd na ot\u00e1zku, \u010di riziko vzniku Alzheimerovej choroby: \u010di rodi\u010dia trpia chorobou alebo \u010di existuje \u0161pecifick\u00fd g\u00e9n APOE. \u00da\u010dastn\u00edci diskutovali o kvalite sp\u00e1nku a odobrali vzorky mozgovomiechovej tekutiny, ktor\u00e9 boli testovan\u00e9 na biologick\u00e9 patol\u00f3gie.\u00a0\t\tV\u00fdskumn\u00edci zistili, \u017ee \u013eudia, ktor\u00ed ohl\u00e1sili zhor\u0161enie sp\u00e1nku z r\u00f4znych d\u00f4vodov, probl\u00e9my so zasp\u00e1van\u00edm a dennou ospalos\u0165ou zv\u00fd\u0161ili hladinu Alzheimerovej choroby v mozgovomiechovej tekutine, to znamen\u00e1, \u017ee sa objavili charakteristick\u00e9 \u010dastice amyloidn\u00fdch prote\u00ednov, tau prote\u00ednov a signaliza\u010dn\u00fdch molek\u00fal po\u0161kodenia buniek mozgu a z\u00e1palovej reakcie. Nie je zauj\u00edmav\u00e9, \u017ee sa nezistila \u017eiadna spojitos\u0165 medzi zmenami cerebrospin\u00e1lnej tekutiny a ob\u0161truk\u010dnou sp\u00e1nkovou apnoe.\t\tV\u00fdsledky zostali rovnak\u00e9 aj vtedy, ke\u010f v\u00fdskumn\u00ed pracovn\u00edci upravili \u010fal\u0161ie faktory, ktor\u00e9 by mohli ovplyvni\u0165 v\u00fdsledok: napr\u00edklad pou\u017eitie spac\u00edch piluliek, vzdelanie, sympt\u00f3my depresie alebo index telesnej hmotnosti.\u00a0\t\tAutori druh\u00e9ho \u010dl\u00e1nku z lek\u00e1rskej fakulty University of Washington v St. Louis, Medical Center \u0161tudovali\u00a0 17 zdrav\u00fdch dospel\u00fdch vo veku 35 a\u017e 65 rokov bez probl\u00e9mov so sp\u00e1nkom alebo kognit\u00edvnych por\u00fach. Ka\u017ed\u00fd \u00fa\u010dastn\u00edk mal na svojom z\u00e1p\u00e4st\u00ed n\u00e1ramok na dva t\u00fd\u017edne, ktor\u00fd monitoroval ich\u00a0 \u010dinnos\u0165 a meral, ko\u013eko \u010dasu spali ka\u017ed\u00fa noc.\u00a0\t\tPo piatich alebo viacer\u00fdch po sebe nasleduj\u00facich d\u0148och dobrovo\u013en\u00edci str\u00e1vili noc v laborat\u00f3riu. V miestnosti, kde spali, vl\u00e1dla temnota, bola zvukov\u00e1 izol\u00e1cia, klimatiz\u00e1cia a priestrannos\u0165 – v\u0161etky podmienky pre perfektn\u00fd sp\u00e1nok. \u013dudia nosia sl\u00fachadl\u00e1 a elektr\u00f3dy boli pripojen\u00e9 k hlave, aby monitorovali mozgov\u00e9 vlny.\t\tAutori poznamen\u00e1vaj\u00fa, \u017ee s\u00fa najviac znepokojen\u00ed t\u00fdmi, ktor\u00ed maj\u00fa probl\u00e9my s chronick\u00fdm sp\u00e1nkom. Teraz je vedecky potvrden\u00e9, \u017ee to m\u00f4\u017ee vies\u0165 k chronick\u00e9mu zv\u00fd\u0161eniu hlad\u00edn amyloidu. Ale mnoh\u00e9 \u0161t\u00fadie na zvierat\u00e1ch uk\u00e1zali, \u017ee ide o priamu cestu k vzniku amyloidov\u00fdch plakov a Alzheimerovej choroby.                                                                                                                                                                                                                                                                                                                                                                                        4.2\/5 - (13 votes)        "},{"@context":"https:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"name":"Nedostatok sp\u00e1nku – priama cesta k Alzheimerovej chorobe","item":"https:\/\/www.zipava.sk\/nedostatok-spanku-priama-cesta-k-alzheimerovej-chorobe\/#breadcrumbitem"}]}]